This is a mp3 player not a quicktime player if I understood that it does not need quick time.

You use the menu button navigate to the play music button and press menu to select, then it plays wherever you left off, then use the left and right direction buttons to scroll to the next one back or next one forward.

When you are in the menu mode, you can use the left and right direction buttons to scroll to the folder icon and use the menu as the select and it will descend to you folders.

I know it sounds complicated but once you use it a couple of times, it will come easy. And the play and pause key becomes cancel or escape key when you are in menu mode.

But if you say you want to play when the MA566 is connected to the pc, then you should use the MTP mode turn the MA566 as a thumb drive, I found it is much simpler and less confusion - Winodws itself gets confused very easily.

Then you just navigate to the thumb drive to the songs and click to play them.

** Important, this is more than a caution, Windows tend to kill thumb drive's FAT table, that is another reason, not safe with Media player or autoplay.
** ALWAYS USE THE GREEN SAFE REMOVAL MODE TO STOP THE THUMB DRIVE BEFORE REMOVING ANY THUMB DRIVE FROM A LIVE WINDOW SESSION - OR ELSE TURN OFF THE ENTIRE COMPUTER BEFORE REMOVAL.
** WINDOWS KEEPS THE FILE ALLOCATION TABLE, AND KEEP A +5VDC TO THE THUMB DRIVE. BY CHOOSING THE SAFE REMOVAL, WINDOWS WILL FLUSH AND REWRITE THE FAT TABLE, AND STOP THE +5VDC NOT TO GO TO THE THUMB DRIVE SO THAT YOU CAN REMOVE ONCE IF POP-UP TO SAY == SAFE TO REMOVE.

i hope it helps, and believe me, first time disconnect may be luck if it still works, second time, again super luck, but many people didn't even get the first chance.

I am not responsible for any damages or data loss.