I disconnected my maxtor basics 500gb from my laptop to use it on a different machine. The other machine would not read and when I reconnected to the original laptop that wont read it either
Computers & Internet - Maxtor
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Answers & Comments
My guess is that something "bad" happened (electrical surge???) when you first disconnected it.
Your only option is to assume that the USB-to-disk-drive adapter inside the casing has failed. So, open the case, remove the disk-drive, and connect the disk-drive to another computer, and see if the drive itself is still "readable". If so, copy all the files, onto the other computer, or burn some DVD disks.