It's never 100% "safe" to update even with good drivers. You'll want to take precautions like making sure you have a backup copy of the old drivers just in case something goes wrong and you are not able to revert to the old drivers. As long as you are getting the drivers off of the official website for the exact card you have, and the operating system you are using is supported, it's usually pretty safe.
Answers & Comments
It's never 100% "safe" to update even with good drivers. You'll want to take precautions like making sure you have a backup copy of the old drivers just in case something goes wrong and you are not able to revert to the old drivers. As long as you are getting the drivers off of the official website for the exact card you have, and the operating system you are using is supported, it's usually pretty safe.