Before you can communicate with your computer you must run CruzSync from the desktop. There are some driver files that must be sent from cruz to point the way to the reader. After you do this it should connect every time. Some time you will have to pull the USB out and put it back end, especially if the reader or the computer has just woke up from a sleep or hibernation mode. ZumoDrive is the account you must set up when you click or press on CruzSync to make all of this happen. Hope this helps